Advancing National Action Plans on Antimicrobial Resistance amidst Health Financing Challenges
By Afreenish Amir
The South Centre held a webinar on advancing national action plans (NAPs) on Antimicrobial Resistance (AMR) amidst health financial challenges, on 20 March 2025. The webinar brought together various national focal point leads for NAPs on AMR and international experts.
Advancing International Cooperation under the Global Digital Compact
By Danish
Bridging the global digital divide in new and emerging technologies, particularly Artificial Intelligence, will require developing countries to strongly leverage international cooperation to build digital skills, knowledge and gain access to these technologies which can accelerate their digital transformation and sustainable development. This emphasis on international cooperation is also deeply embedded in the Global Digital Compact, which was adopted as part of the Pact for the Future. This paper therefore looks at how international cooperation modalities have been included in the GDC across the different issue areas, how developing countries are already engaging with the GDC through their national initiatives, and provides some useful considerations going forward.
Will the Global Digital Compact ensure an equitable future for Developing Countries?
By Daniel Uribe
The Global Digital Compact (GDC), adopted by the United Nations General Assembly in 2024, aims to establish a framework for equitable digital transformation, particularly for developing countries. While the GDC acknowledges the importance of human rights, bridging the digital divide, and ensuring a just transition, it faces significant challenges in addressing structural inequalities and implementing robust accountability mechanisms. This paper examines the GDC’s potential to foster an inclusive digital future, highlighting the necessity of addressing fundamental rights, promoting business accountability through a legally binding instrument, and recognising the interconnectedness of digital inclusion with access to essential resources like energy, education, and healthcare.
As the World Trade Organization (WTO) marks its 30th anniversary, Director-General (DG) Ngozi Okonjo-Iweala has called for a reflection process to assess the organisation’s achievements and chart its future. For developing countries, this reflection presents a significant opportunity. A well-managed process could begin to address the structural imbalances embedded in WTO rules that constrain policy space, limit technology access, and restrict development pathways. Conversely, a poorly handled approach risks reducing it to a narrow review that fails to account for the broader economic realities shaping trade and the persistent development needs of the Global South. This paper argues that the DG’s reflection process must be firmly member-driven, with clear governance principles, and rooted in a comprehensive development audit to assess how WTO rules have impacted developing countries over the past three decades. The paper contends that a meaningful reflection requires more than procedural introspection; it requires a serious conversation about the future of global trade governance and its relevance to development, ensuring that the WTO’s evolution genuinely responds to the priorities of its majority membership.
Application de l’Exception Bolar: Différentes approches dans le droit de l’UE
Par Dmytro Doubinsky
Ce Document de recherche aborde le problème toujours plus aigu de l’accès aux médicaments essentiels, en se concentrant sur le rôle des droits de propriété intellectuelle, en particulier les droits de brevet, qui restreignent l’accès en permettant des monopoles sur le marché pharmaceutique qui maintiennent les prix des médicaments à un niveau élevé. Le document explore l’exception Bolar, un mécanisme juridique conçu pour permettre aux fabricants de médicaments génériques de demander l’approbation réglementaire avant l’expiration d’un brevet, empêchant ainsi l’extension de facto des monopoles de brevets. L’étude examine la transformation de l’exception Bolar d’un cas juridique spécifique en un instrument important en matière de droit de la propriété intellectuelle, de droit commercial et de droit pharmaceutique. Elle analyse les principaux cadres juridiques internationaux et les directives européennes relatifs à l’exception Bolar et met en évidence les interprétations divergentes de l’exception dans les jurisprudences allemande et polonaise. Grâce à cette analyse comparative, le document encourage une mise en œuvre plus large des exceptions Bolar afin d’améliorer l’accès à des médicaments abordables et de réduire les coûts des soins de santé.
Contribución del Centro Sur al Informe del Secretario General de las Naciones Unidas sobre la aplicación de la Resolución A/RES/79/7 de la Asamblea General sobre la “Necesidad de poner fin al bloqueo económico, comercial y financiero impuesto por los Estados Unidos de América contra Cuba”
Esta contribución del Centro Sur se presenta en respuesta a la solicitud del Secretario General como un aporte al informe del Secretario General de acuerdo a la resolución A/RES/79/7, con respecto a la imposición de medidas económicas, financieras y comerciales unilaterales por parte de los Estados Unidos de América, contra Cuba, en violación de los principios básicos de la Carta de las Naciones Unidas y el Derecho Internacional.
Leveraging the Antimicrobial Resistance Declarations of 2024 to Reduce the Burden of Drug-Resistant Infections
By Afreenish Amir & Viviana Munoz Tellez
In 2024, two significant events highlighted the global concern about antimicrobial resistance (AMR). AMR is a pressing global health issue, imperiling public health, economic stability, and societal well-being. The 79th United Nations General Assembly (UNGA) in its special session on AMR and the 4th Ministerial Meeting on AMR have emphasized the need for collective action and international cooperation to mitigate the impact of AMR. The UNGA Declaration has set some targets including reducing global deaths associated with bacterial AMR by 10% by 2030 and enhancing the antimicrobial usage from the World Health Organization (WHO) AWaRe (Access, Watch, Reserve) Access category to 70% by 2030. Accomplishing these targets requires enhancing the inter-ministerial and inter-sectoral collaboration within countries, and the development of strategies reflected in national action plans (NAPs) tailored to each country’s unique dynamics. There are several important commitments made that now need to be implemented, including increased support to countries to develop funded NAPs, the establishment of an Independent Panel on Evidence for Action against AMR, capacity building for local manufacturing of vaccines, therapeutics, diagnostics and essential supplies, developing a new Global Action Plan on AMR by 2026 with a focus on a people centered approach, and advancing cross-sectoral behavioral change interventions. However, these fell short of ambition, particularly in key areas such as financing, reduction of misuse and overuse of antimicrobials in human and animal health and the environment as a vector for AMR. This Policy Brief reviews the new commitments on AMR made in 2024 under the light of current challenges in developing countries and advances recommendations to accelerate progress on AMR.
Unifying Efforts against Antimicrobial Resistance: Supporting Collective Efforts During WAAW 2024
By Francesca Chiara
Antimicrobial Resistance (AMR) is an escalating global health challenge, demanding urgent and coordinated efforts. During World AMR Awareness Week (WAAW) 2024, 27 impactful projects targeting more than 20 countries across Africa, Asia and Latin America amplified the theme “Educate, Advocate, Act Now.” The projects were selected by the South Centre for funding, with support of the United Kingdom Fleming Fund. This is the third year this financial support is offered to selected Civil Society Organization (CSO) projects, based on a call for applications.
These initiatives directly reached over 3000 individuals through training sessions, workshops, and targeted advocacy campaigns. Many more were engaged through social media and grassroots activities. This overview highlights the transformative impact of these campaigns.
This paper argues that the global capitalist economy has been and is built on the monopolization of advanced technological knowledge through trade secrets and intellectual property rights protection, controlled by companies and countries of the Global North. Companies and countries in the Global South use commoditized knowledge or knowledge in the commons. In the colonial period this was largely confined to the production of agricultural commodities and now to carry out the bulk of production functions. This division of knowledge and the difference in returns to monopolized knowledge and knowledge in the commons drives global inequality. The paper points out that countries of the Global South that moved out of the middle-income trap did so by advancing from just using knowledge to also creating knowledge. Finally, it argues that there is a need to reform the system of intellectual property rights in order to promote inclusion and not exclusion.
Inputs to Inform the Thematic Report of the Special Rapporteur on the Promotion and Protection of Human Rights in the Context of Climate Change to the Human Rights Council 59th session
South Centre
February 2025
The South Centre calls for a Just Transition away from fossil fuels, centering the rights of marginalized communities & the principle of common but differentiated responsibilities.
Will the Pact for the Future Advance a Common Global Agenda on the Challenges Facing Humanity?
By Viviana Munoz Tellez, Danish, Abdul Muheet Chowdhary, Nirmalya Syam, Daniel Uribe
At a time when multilateralism is needed more than ever to address the global challenges and rising geopolitical tensions, paradoxically, the capacity and delegated power of the United Nations (UN) to uphold a rule-based order to keep peace and security is being weakened. Even in an increasingly multipolar world, a retreat towards unilateralism by world powers masked as national sovereignty is dangerous and highly unfavourable for developing countries. In this light, the United Nations Pact for the Future, a new forward-looking agenda of commitments adopted by consensus by UN Member States in September 2024, is a welcome initiative. The Pact for the Future, nonetheless, is short in delivering commitments on transformative changes in global governance and solutions to the most pressing global challenges. This document briefly examines some of the actions and high-level commitments in the Pact of the Future to strengthen multilateral cooperation and provides recommendations for their implementation.
Lessons from COVID-19: Strengthening Antimicrobial Stewardship Prior and During Pandemics
By Dr Rasha Abdelsalam Elshenawy
The COVID-19 pandemic has had a complex impact on the silent pandemic of antimicrobial resistance (AMR). While increased antibiotic misuse and disrupted antimicrobial stewardship (AMS) programs exacerbated AMR in some settings, heightened awareness and improved infection prevention measures implemented to control COVID-19 provided valuable lessons on sustaining these practices in the fight against AMR. This brief highlights lessons learned from the pandemic, such as the importance of access to antimicrobials and the urgent need for resilient and sustainable AMS integrated into pandemic preparedness, strengthening infection prevention and surveillance systems, enhancing access and use of diagnostics, and promoting a One Health approach. By leveraging these lessons, policymakers can build more resilient health systems, maintain the effectiveness of antimicrobials and be better prepared for future pandemics, particularly in developing countries. Immediate action is essential to protect public health and combat AMR effectively.